Torque Teno Virus (TTV) and Epstein–Barr Virus (EBV) Viral Load in Peripheral Blood as a Biomarker of “Net Immunosuppression”: Factors Influencing Viral Load in Adult Patients Awaiting Solid Organ Transplantation
نویسندگان
چکیده
2354. Torque Teno Virus (TTV) and Epstein–Barr Virus (EBV) Viral Load in Peripheral Blood as a Biomarker of “Net Immunosuppression”: Factors Influencing Viral Load in Adult Patients Awaiting Solid Organ Transplantation Jutta Preiksaitis, MD, FRCP (C); Curtis Mabilangan, BSc; Yupin Tong, PhD; Catherine Burton, MD MSc and Simon Urschel, MD; Medicine, Infectious Diseases, University of Alberta, Edmonton, AB, Canada, Pediatrics, Infectious Diseases, University of Alberta, Edmonton, AB, Canada, Pediatrics, Cardiology, University of Alberta, Edmonton, AB, Canada
منابع مشابه
Epstein-Barr virus gene expression in the peripheral blood of transplant recipients with persistent circulating virus loads.
Pediatric solid organ transplant recipients are at risk for Epstein-Barr virus (EBV)-driven lymphoproliferative disease. The expression of 5 sentinel EBV genes (EBNA1, EBNA2a, LMP1, LMP2a, and ZEBRA) was examined in solid organ transplant recipients who developed persistent virus loads in their peripheral blood lymphocytes after transplantation. Two distinct groups were identified. LMP2a gene e...
متن کاملThe relationship between Human Papillomavirus and Epstein-Barr virus infections with breast cancer of Iranian patients
Background: Breast cancer is the malignancy in humans and other mammals. Several risk factors are involved in their appearance such as higher hormone levels and obesity. Identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. Viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...
متن کاملInfusion of autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for prevention of EBV-related lymphoproliferative disorder in solid organ transplant recipients with evidence of active virus replication.
Epstein-Barr virus (EBV)-associated posttransplantation lymphoproliferative disorders (PTLDs) are a well-recognized complication of immunosuppression in solid organ transplant recipients. The reported therapeutic approaches are frequently complicated by rejection, toxicity, and other infectious pathologies, and overall mortality in patients with unresponsive PTLD remains high. Thus, low-toxicit...
متن کاملGenotypic Detection of Epstein Barr Virus in Pediatric Transplant Recipients From India.
OBJECTIVE To determine the rate of occurrence and genotypes of Epstein-Barr Virus (EBV) among pediatric renal and liver transplants recipients. DESIGN Observational study. SETTING Vision Research Foundation referral center and Institute of Liver Disease and Transplantation, Chennai, India. PARTICIPANTS 70 pediatric solid organ transplant recipients and 60 voluntary healthy donors. METHO...
متن کاملDetection of cytomegalovirus, Epstein–Barr virus, and Torque Teno virus in subgingival and atheromatous plaques of cardiac patients with chronic periodontitis
Background Periodontitis and atherosclerosis represent a chronic inflammatory process. The incidence of periodontitis in cardiac patients with atherosclerosis is a well-established fact. The role of viruses in the etiopathogenesis of both has been proposed. Aim The aim of the study was to evaluate the prevalence of Torque Teno virus (TTV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV) i...
متن کامل